Article
An HLA class II locus, previously identified by a genome-wide association study, is also associated with susceptibility to pulmonary tuberculosis in a Chinese population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2018
Miao Ruifen, Huang Shuran, Li Chen, Ding Songning, Wang Rong, Xu Ke, Yang Chen, Xu Fei, Ge Haibo
Abstract excerpt
OBJECTIVE: Genome-wide association study (GWAS) in Icelanders identified HLA class II sequence variants on chromosome 6p21 as tuberculosis (TB) susceptibility loci. To evaluate the role of these loci in other populations with different ancestry, we conducted a case-control study in Chinese population. METHODS: We genotyped two genetic variants (rs9272461 and rs9271300) on the reported chromosome 6p21 in 739...
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