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Article

p53 mutations in classic and pleomorphic invasive lobular carcinoma of the breast.

Cellular oncology (Dordrecht, Netherlands) - 1 Apr 2012

Ercan Cigdem, van Diest Paul J, van der Ende Bram, Hinrichs John, Bult Peter, Buerger Horst, van der Wall Elsken, Derksen Patrick W B

Abstract excerpt

BACKGROUND: p53 is a tumor suppressor that is frequently mutated in human cancers. Although alterations in p53 are common in breast cancer, few studies have specifically investigated TP53 mutations in the breast cancer subtype invasive lobular carcinoma (ILC). Recently reported conditional mouse models have indicated that functional p53 inactivation may play a role in ILC development and progression. Since...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22354696
DOI: 10.1007/s13402-012-0071-y
PMCID: PMC3306558

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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