Article
Lack of association of ADH1C genotype with breast cancer susceptibility in Caucasian population: a pooled analysis of case-control studies.
Breast (Edinburgh, Scotland) - 1 Aug 2012
Wang Liping, Zhang Ying, Ding Dapeng, He Xiaofeng, Zhu Zhenglan
Abstract excerpt
PURPOSE: Recent epidemiological studies demonstrated that alcohol dehydrogenase 1C (ADH1C) alleles that result in acetaldehyde accumulation in the cells can enhance a drinker's risk of developing alcohol related cancer in a variety of tissues. The published data on the association between ADH1C alleles and breast cancer occurrence in Caucasians have led to in contradictory results. This meta-analysis of...
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