Article
Alcohol metabolism, alcohol intake, and breast cancer risk: a sister-set analysis using the Breast Cancer Family Registry.
Breast cancer research and treatment - 1 Dec 2007
Terry Mary Beth, Knight Julia A, Zablotska Lydia, Wang Qiao, John Esther M, Andrulis Irene L, Senie Ruby T, Daly Mary, Ozcelik Hilmi, Briollais Laurent, Santella Regina M
Abstract excerpt
Moderate alcohol intake has been consistently associated with a modest (30-50%) increase in breast cancer risk, but it remains unclear if certain individuals have higher susceptibility to the harmful effects of alcohol intake. Individuals differ in their ability to metabolize alcohol through genetic differences in alcohol dehydrogenase (ADH), the enzyme that catalyzes the oxidation of approximately 80% of ethanol...
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