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Article

Investigation of a possible relationship between EPHX1 gene polymorphisms and colorectal cancer in Turkish society.

Genetic testing and molecular biomarkers - 1 May 2012

Sahin Onder, Arikan Soykan, Oltulu Yasemin Musteri, Coskunpinar Ender, Eren Ayşe, Cacina Canan, Guler Erkan, Yaylim Ilhan

Abstract excerpt

Metabolism of chemical carcinogens, including their activation and detoxification, plays a key role in carcinogenesis. Microsomal epoxide hydrolase (EPHX1) has an important role in the metabolism of polycyclic aromatic hydrocarbons and detoxification of procarcinogens. The aim of this study was to investigate the association between colorectal cancer (CRC) development and EPHX1 gene polymorphisms. We investigated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22352736
DOI: 10.1089/gtmb.2011.0223

Genes

EPHX1

Provenance

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Investigation of a possible relationship between EPHX1 gene polymorphisms and colorectal cancer in Turkish society.PMID 22352736Read ↗

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Quantitative assessment of the influence of EPHX1 gene polymorphisms and cancer risk: a meta-analysis with 94,213 subjects.Semantic proximity Read ↗

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Role of epoxide hydrolase 1 gene polymorphisms in esophageal cancer in a high-risk area in India.Semantic proximity Read ↗

Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer.Semantic proximity Read ↗

Meta-analysis demonstrates lack of an association of microsomal epoxide hydrolase 1 polymorphisms with esophageal cancer risk.Semantic proximity Read ↗

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