Article
Immunological relationships during primary infection with Heligmosomoides polygyrus. Regulation of fast response phenotype by H-2 and non-H-2 genes.
Parasitology - 1 Sept 1993
Wahid F N, Behnke J M
Abstract excerpt
The inheritance of response phenotype to Heligmosomoides polygyrus was investigated in F1 hybrid progeny of fast and slow responder mouse strains. The fast responses of SJL(H-2s) and SWR(H-2q) mice were mediated by dominant genes complementing each other in F1 hybrids which lost worms earlier and...
Topics
- Animals
- Antibodies, Helminth
- Enzyme-Linked Immunosorbent Assay
- Gene Expression Regulation
- H-2 Antigens
- Immunity, Innate
- Immunoglobulin G
- Mice
- Mice, Inbred C57BL
- Nematospiroides dubius
- Phenotype
- Strongylida Infections
- Time Factors