Article
Immunological relationships during primary infection with Heligmosomoides polygyrus. Regulation of fast response phenotype by H-2 and non-H-2 genes.
Parasitology - 1 Sept 1993
Wahid F N, Behnke J M
Abstract excerpt
The inheritance of response phenotype to Heligmosomoides polygyrus was investigated in F1 hybrid progeny of fast and slow responder mouse strains. The fast responses of SJL(H-2s) and SWR(H-2q) mice were mediated by dominant genes complementing each other in F1 hybrids which lost worms earlier and produced faster parasite-specific IgG1 antibody responses than either parent. However, the response of F1 hybrids from...
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