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HLA-B*1511 is a risk factor for carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients.

Epilepsia - 1 Dec 2010

Kaniwa Nahoko, Saito Yoshiro, Aihara Michiko, Matsunaga Kayoko, Tohkin Masahiro, Kurose Kouichi, Furuya Hirokazu, Takahashi Yukitoshi, Muramatsu Masaaki, Kinoshita Shigeru, Abe Masamichi, Ikeda Hiroko, Kashiwagi Mariko, Song Yixuan, Ueta Mayumi, Sotozono Chie, Ikezawa Zenro, Hasegawa Ryuichi

Abstract excerpt

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life-threatening severe cutaneous adverse reactions. Recently, strong associations of HLA-B*1502 with carbamazepine-induced SJS/TEN have been found in Han Chinese patients. These associations have been confirmed in several Asian populations, excluding Japanese. SJS patients carrying HLA-B*1508, HLA-B*1511, or HLA-B*1521, which are...

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PMID: 21204807
DOI: 10.1111/j.1528-1167.2010.02766.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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