Article
Angiotensin converting enzyme insertion/deletion (I/D) (rs4646994) and Vegf polymorphism (+405G/C; rs2010963) in type II diabetic patients: Association with the risk of coronary artery disease.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Sept 2015
Moradzadegan Atousa, Vaisi-Raygani Asad, Nikzamir Abdolrahim, Rahimi Zohreh
Abstract excerpt
HYPOTHESIS: Little is known about the concomitant presence of the angiotensin-converting enzyme (ACE) (rs4646994) D allele and vascular endothelial growth factor(VEGF) (+405G/C; rs2010963) G allele on the susceptibility of coronary artery disease (CAD). Here we examined the hypothesis that ACE-D and VEGF-G alleles act synergistically to increase the severity of CAD in patients with type II diabetes mellitus...
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