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Article

Synergism between paraoxonase Arg 192 and the angiotensin converting enzyme D allele is associated with severity of coronary artery disease.

Molecular biology reports - 1 Mar 2012

Vaisi-Raygani Asad, Rahimi Zohreh, Tavilani Haidar, Vaisi-Raygani Hadiss, Kiani A, Aminian M, Shakiba E, Shakiba Y, Pourmotabbed Tayebeh

Abstract excerpt

We have previously shown that angiotensin-converting enzyme (ACE) gene D allele is an independent risk factor for early onset coronary artery disease (CAD). Little is known about the concomitant presence of the ACE gene D allele and paraoxonase (PON1) codon 192 arginine (Arg) on the severity of CAD. Regarding the high rate of CAD among Iranians the aim of present study was to examine the hypothesis of synergistic...

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Source

Identifiers

PMID: 21681430
DOI: 10.1007/s11033-011-1027-4

Genes

CAD
ACE
PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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