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Article

Polymorphism and synergism of angiotensin-converting enzyme (ACE) and plasminogen activator inhibitor-1 (PAI-1) genes in coronary artery disease.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2015

Sakhteh Maryam, Poopak Behzad, Amirizadeh Naser, Shamshiri Ahmadreza, Bagheri Abdolhamid, Faranoush Mohammad

Abstract excerpt

INTRODUCTION: Among the genetic factors for coronary artery diseases, PAI-1 4G/5G and ACE I/D polymorphisms can be noted. This study was carried out to investigate the association of these two polymorphisms and their synergism in coronary artery disease (CAD) from a sample of the Iranian population. MATERIALS AND METHODS: Sixty-one patients with a history of CAD and 92 healthy controls participated in our study....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25501306
DOI: 10.1177/1470320314561247

Genes

ACE
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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