Article
Genome-wide association analysis of copy number variation in recurrent depressive disorder.
Molecular psychiatry - 1 Feb 2013
Rucker J J H, Breen G, Pinto D, Pedroso I, Lewis C M, Cohen-Woods S, Uher R, Schosser A, Rivera M, Aitchison K J, Craddock N, Owen M J, Jones L, Jones I, Korszun A, Muglia P, Barnes M R, Preisig M, Mors O, Gill M, Maier W, Rice J, Rietschel M, Holsboer F, Farmer A E, Craig I W, Scherer S W, McGuffin P
Abstract excerpt
Large, rare copy number variants (CNVs) have been implicated in a variety of psychiatric disorders, but the role of CNVs in recurrent depression is unclear. We performed a genome-wide analysis of large, rare CNVs in 3106 cases of recurrent depression, 459 controls screened for lifetime-absence of psychiatric disorder and 5619 unscreened controls from phase 2 of the Wellcome Trust Case Control Consortium (WTCCC2)....
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