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Article

Two cation transporters Ena1 and Nha1 cooperatively modulate ion homeostasis, antifungal drug resistance, and virulence of Cryptococcus neoformans via the HOG pathway.

Fungal genetics and biology : FG & B - 1 Apr 2012

Jung Kwang-Woo, Strain Anna K, Nielsen Kirsten, Jung Kwang-Hwan, Bahn Yong-Sun

Abstract excerpt

Maintenance of cation homeostasis is essential for survival of all living organisms in their biological niches. It is also important for the survival of human pathogenic fungi in the host, where cation concentrations and pH will vary depending on different anatomical sites. However, the exact role of diverse cation transporters and ion channels in virulence of fungal pathogens remains elusive. In this study we...

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Identifiers

PMID: 22343280
DOI: 10.1016/j.fgb.2012.02.001
PMCID: PMC3319253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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