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Article

A community-based study of nucleotide excision repair polymorphisms in relation to the risk of non-melanoma skin cancer.

The Journal of investigative dermatology - 1 May 2012

Wheless Lee, Kistner-Griffin Emily, Jorgensen Timothy J, Ruczinski Ingo, Berthier-Schaad Yvette, Kessing Bailey, Hoffman-Bolton Judith, Francis Lesley, Shugart Yin Yao, Strickland Paul T, Kao W H Linda, Alani Rhoda M, Smith Michael W, Alberg Anthony J

Abstract excerpt

Nucleotide excision repair (NER) is responsible for protecting DNA in skin cells against UVR-induced damage. Using a candidate pathway approach, a matched case-control study nested within a prospective, community-based cohort was carried out to test the hypothesis that single-nucleotide polymorphisms (SNPs) in NER genes are associated with susceptibility to non-melanoma skin cancer (NMSC). Histologically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22336945
DOI: 10.1038/jid.2012.4
PMCID: PMC3326207

Genes

ERCC6

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