Article
TP53 gene status and human papilloma virus infection in response to platinum plus taxane-based chemotherapy of epithelial ovarian carcinomas.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Malisic E, Jankovic R, Jakovljevic K, Radulovic S
Abstract excerpt
PURPOSE: Lack of symptoms in early stages of disease and resistance to chemotherapy make epithelial ovarian carcinomas one of the most lethal neoplasms among gynaecological malignancies. The aim of this study was to analyse the impact of TP53 mutations, codon 72 polymorphism and human papillomavirus (HPV) infection on the response to platinum-taxane combination chemotherapy in patients with epithelial ovarian...
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