Article
Pathologic evaluation of the solid variant of aneurysmal bone cysts with USP6 rearrangement with an emphasis on the frequent diagnostic pitfalls.
Pathology international - 1 Aug 2020
Zhou Jun, Zheng Saifang, Zhou Luting, Yong Xiang, Zhang Yanping, QinXia, Zhang Wenjing, Wang Chaofu
Abstract excerpt
The solid variant of aneurysmal bone cyst (SVABC) is very uncommon and frequently misdiagnosed. We reevaluated and summarized the clinicopathologic features of 17 SVABCs and further discussed the use of this nomenclature to differ SVABCs from extragnathic giant cell reparative granuloma (GCRG) in the setting of the USP6 rearrangement era. The immunohistochemical markers included α-SMA, SATB2, AE1/AE3, Ki67, S100,...
Topics
- Adolescent
- Adult
- Aged
- Biomarkers, Tumor
- Bone Cysts, Aneurysmal
- Child
- Child, Preschool
- Diagnosis, Differential
- Female
- Granuloma, Giant Cell
- Humans
- Male
- Middle Aged
- Mutation
- Ubiquitin Thiolesterase