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Article

Two separate gene clusters encode the biosynthetic pathway for the meroterpenoids austinol and dehydroaustinol in Aspergillus nidulans.

Journal of the American Chemical Society - 14 Mar 2012

Lo Hsien-Chun, Entwistle Ruth, Guo Chun-Jun, Ahuja Manmeet, Szewczyk Edyta, Hung Jui-Hsiang, Chiang Yi-Ming, Oakley Berl R, Wang Clay C C

Abstract excerpt

Meroterpenoids are a class of fungal natural products that are produced from polyketide and terpenoid precursors. An understanding of meroterpenoid biosynthesis at the genetic level should facilitate engineering of second-generation molecules and increasing production of first-generation compounds. The filamentous fungus Aspergillus nidulans has previously been found to produce two meroterpenoids, austinol and...

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Identifiers

PMID: 22329759
DOI: 10.1021/ja209809t
PMCID: PMC3350773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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