Article
Phosphopantetheinyl transferase CfwA/NpgA is required for Aspergillus nidulans secondary metabolism and asexual development.
Eukaryotic cell - 1 Apr 2007
Márquez-Fernández Olivia, Trigos Angel, Ramos-Balderas Jose Luis, Viniegra-González Gustavo, Deising Holger B, Aguirre Jesús
Abstract excerpt
Polyketide synthases (PKSs) and/or nonribosomal peptide synthetases (NRPSs) are central components of secondary metabolism in bacteria, plants, and fungi. In filamentous fungi, diverse PKSs and NRPSs participate in the biosynthesis of secondary metabolites such as pigments, antibiotics, siderophores, and mycotoxins. However, many secondary metabolites as well as the enzymes involved in their production are yet to...
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