Article
The branched-chain amino acid aminotransferase encoded by ilvE is involved in acid tolerance in Streptococcus mutans.
Journal of bacteriology - 1 Apr 2012
Santiago Brendaliz, MacGilvray Matthew, Faustoferri Roberta C, Quivey Robert G
Abstract excerpt
The ability of Streptococcus mutans to produce and tolerate organic acids from carbohydrate metabolism represents a major virulence factor responsible for the formation of carious lesions. Pyruvate is a key metabolic intermediate that, when rerouted to other metabolic pathways such as amino acid...
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