PDGFRA promoter polymorphisms are associated with the risk of papillary             thyroid cancer.

doi:10.3892/mmr.2012.784

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Article

PDGFRA promoter polymorphisms are associated with the risk of papillary thyroid cancer.

Molecular medicine reports - 1 May 2012

Kim Mi-Ja, Kim Su Kang, Park Hae Jeong, Chung Dae Han, Park Hyun-Kyung, Lee Jong Seok, Kwon Kee Hwan, Chung Joo-Ho

Abstract excerpt

Platelet-derived growth factor (PDGF) acts as a regulator in cancer development and progression. We investigated whether single nucleotide polymorphisms (SNPs) of platelet-derived growth factor receptor α polypeptide (PDGFRA) and platelet-derived growth factor receptor β polypeptide (PDGFRB) genes are associated with papillary thyroid cancer (PTC) in a Korean population. Two promoter SNPs (rs6554162, -1309A/G and...

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Identifiers

PMID: 22327316
DOI: 10.3892/mmr.2012.784

Genes

PDGFRA
PDGFRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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