Article
Association of the T1799A BRAF mutation with tumor extrathyroidal invasion, higher peripheral platelet counts, and over-expression of platelet-derived growth factor-B in papillary thyroid cancer.
Endocrine-related cancer - 1 Mar 2008
Wang Yangang, Ji Meiju, Wang Wei, Miao Zhimin, Hou Peng, Chen Xinyan, Xu Feng, Zhu Guangwu, Sun Xianlu, Li Yujun, Condouris Steven, Liu Dingxie, Yan Shengli, Pan Jie, Xing Mingzhao
Abstract excerpt
The relationship among BRAF mutation, platelet counts, and platelet-derived growth factor (PDGF) with respect to clinicopathological outcomes of papillary thyroid cancer (PTC) may play a role in PTC pathogenesis but remains undefined. We examined the T1799A BRAF mutation by direct genomic DNA seq...
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