Article
Associations between promoter polymorphism -106A/G of interleukin-11 receptor alpha and papillary thyroid cancer in Korean population.
Surgery - 1 Feb 2012
Eun Young Gyu, Shin Il Ho, Kim Mi-Ja, Chung Joo-Ho, Song Jeong Yoon, Kwon Kee Hwan
Abstract excerpt
BACKGROUND: The interleukin11 (IL11) and IL11 receptor alpha (IL11RA) are involved in cellular growth, differentiation, invasiveness, and tumor progression in several tumors. We investigated whether coding single nucleotide polymorphisms (cSNPs) of IL11 and promoter SNP IL11RA would contribute to the development of papillary thyroid cancer (PTC). We also assessed the relationships between IL11 and IL11RA SNPs and...
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