Article
Association study of integrins beta 1 and beta 2 gene polymorphism and papillary thyroid cancer.
American journal of surgery - 1 Jun 2013
Eun Young Gyu, Kim Su Kang, Chung Joo-Ho, Kwon Kee Hwan
Abstract excerpt
BACKGROUND: We investigated whether single nucleotide polymorphisms (SNPs) of integrin beta 1 (ITGB1) and integrin beta 2 (ITGB2) contribute to the development of papillary thyroid cancer (PTC). METHODS: Two synonymous SNPs (rs2230396 and rs2298141) of ITGB1 and 1 synonymous SNP (rs2352326), 1 5' URT-region SNP (rs2070947), and 1 promoter SNP (rs2070946) of ITGB2 SNPs were genotyped using direct sequencing in 94...
