Article
The fibrillin-Marfan syndrome connection.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Sept 1993
Ramirez F, Pereira L, Zhang H, Lee B
Abstract excerpt
A few years ago no one would have suspected that the well-known disorder of connective tissue, Marfan syndrome, could be caused by mutations in a recently discovered extracellular component, fibrillin. Likewise, nobody would have predicted that fibrillin represents a small family of proteins that...
Topics
- Connective Tissue
- Extracellular Matrix
- Fibrillins
- Humans
- Incidence
- Marfan Syndrome
- Microfilament Proteins
- Mutation
- Protein Structure, Tertiary