Derivation of male germ cells from induced pluripotent stem cells <i>in vitro</i> and in reconstituted seminiferous tubules

Abstract excerpt

OBJECTIVES: Previous studies have demonstrated that mouse- and human-induced pluripotent stem (iPS) cells can differentiate into primordial germ cells in vitro. However, up to now it is not known whether iPS cells would be able to differentiate into male germ cells in vivo. The aim of this study was to explore differentiation potential of iPS cells to male germ cells in vitro and in vivo. MATERIALS AND METHODS:...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Pluripotent Stem Cells Research
• Share to Reproductive Biology and Fertility
• Share to Sperm and Testicular Function