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In vitro reconstitution of germ cell development†

11 Jul 2019

Abstract excerpt

Germ cell development is a series of highly specialized processes through which diploid pluripotent cells differentiate into haploid gametes. The processes include biologically important events such as epigenetic reprogramming, sex determination, and meiosis. The mechanisms underlying these events are key issues in reproductive and developmental biology, yet they still remain elusive. As a tool to elucidate these...

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PMID: 31295346
DOI: 10.1093/biolre/ioz111

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