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Article

IL1RN genetic variations and risk of IPF: a meta-analysis and mRNA expression study.

Immunogenetics - 1 May 2012

Korthagen Nicoline M, van Moorsel Coline H M, Kazemier Karin M, Ruven Henk J T, Grutters Jan C

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a rare and devastating lung disease of unknown aetiology. Genetic variations in the IL1RN gene, encoding the interleukin-1 receptor antagonist (IL-1Ra), have been associated with IPF susceptibility. Several studies investigated the variable number tandem repeat (VNTR) or single nucleotide polymorphisms rs408392, rs419598 and rs2637988, with variable results. The aim of this...

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Source

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Identifiers

PMID: 22322675
DOI: 10.1007/s00251-012-0604-6
PMCID: PMC3324677

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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