Functional polymorphism in the EpCAM gene is associated with occurrence and advanced disease status of cervical cancer in Chinese population.

doi:10.1007/s11033-012-1560-9

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Functional polymorphism in the EpCAM gene is associated with occurrence and advanced disease status of cervical cancer in Chinese population.

Molecular biology reports - 1 Jul 2012

Hu Min, Jian Lan, Zhang Liyuan, Zheng Jiang, You Yonghe, Deng Jieqiong, Li Hua, Zhou Yifeng

Abstract excerpt

The epithelial cell adhesion molecule (EpCAM) was originally identified as a tumor associated antigen, attributable to its high expression on rapidly proliferating tumors of epithelial origin. EpCAM plays vital roles in carcinogenesis, tumor progression and metastasis in most tumors. A non-synonymous polymorphism (rs1126497 C/T) was found in exon 3 of EpCAM, which cause a transition from 115 Met to 115 Thr....

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PMID: 22322561
DOI: 10.1007/s11033-012-1560-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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