Article
Increased miR‐222 in <i>H. pylori</i>‐associated gastric cancer correlated with tumor progression by promoting cancer cell proliferation and targeting RECK
2 Feb 2012
Abstract excerpt
Little is known about the potential role of microRNAs (miRNAs) in the carcinogenesis of gastric cancer induced by Helicobacter pylori (H. pylori). Here, we showed that microRNA-222 (miR-222) was up-regulated in H. pylori-infected gastric mucosa and gastric cancer. Ectopic expression of miR-222 promoted cell proliferation and colony formation in vitro. Mechanistically, we identified RECK as a novel target of...
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