Article
miR-221 and miR-222 expression increased the growth and tumorigenesis of oral carcinoma cells.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Aug 2011
Yang Chun-Ju, Shen Wilma Grace, Liu Chung-Ji, Chen Yun-Wen, Lu Hsuan-Hsuan, Tsai Meng-Miao, Lin Shu-Chun
Abstract excerpt
BACKGROUNDS: MicroRNAs are small noncoding RNAs involved in posttranscriptional gene regulation, which play an important role in both physiological functioning and pathological progression. The miR-221/miR-222 microRNA family has been shown to be related to the neoplastic process in a number of different types of cancers; nevertheless, its function in oral squamous cell carcinoma (OSCC) remained uncertain....
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