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Article

miR-221 and miR-222 Simultaneously Target RECK and Regulate Growth and Invasion of Gastric Cancer Cells

1 Jan 2015

Abstract excerpt

BACKGROUND: Although Helicobacter pylori infection is necessary for development of gastric adenocarcinoma (GAC), the underlying mechanism remains poorly defined. This study aimed to explore how miR-221 and miR-222 are dysregulated after H. pylori infection and how these 2 miRNAs are involved in pathological development of gastric cancer. MATERIAL AND METHODS: qRT-PCR analysis was performed to quantify miR-221 and...

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PMID: 26364844
DOI: 10.12659/msm.894324

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