Article
Association of GSTM1 and GSTT1 gene deletions with risk of head and neck cancer in Pakistan: a case control study.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2010
Nosheen M, Ishrat M, Malik F A, Baig R M, Kayani M A
Abstract excerpt
Polymorphic deletions of GSTM1 and GSTT1 genes involved in the detoxification of potentially carcinogenic agents may be risk factors for various cancers, including head and neck cancer (HNC). In the present case-control study we aimed to access possible associations of HNC with GSTM1 and GSTT1 null genotypes in a Pakistani population. DNA was extracted from leukocytes of 388 cancer patients and 150 healthy...
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