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Article

Downregulated Dicer expression predicts poor prognosis in chronic lymphocytic leukemia.

Cancer science - 1 May 2012

Zhu Dan-Xia, Fan Lei, Lu Rui-Nan, Fang Cheng, Shen Wen-Yi, Zou Zhi-Jian, Wang Yin-Hua, Zhu Hua-Yuan, Miao Kou-Rong, Liu Peng, Xu Wei, Li Jian-Yong

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is the most common leukemia in the western world. Alterations in microRNAs (miRNAs) expression have been proposed to play a role in CLL pathogenesis. Dicer and Drosha are the main regulators of miRNA biogenesis, and deregulation of their expression has been indicated as a possible cause of miRNA alterations observed in various cancers. To investigate the role of Dicer and Drosha...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Source

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Identifiers

PMID: 22320315
DOI: 10.1111/j.1349-7006.2012.02234.x
PMCID: PMC7659218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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