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Article

The Significance of RHD Genotyping and Characteristic Analysis in Chinese RhD Variant Individuals.

Frontiers in immunology - 1 Jan 2021

Ying Yanling, Zhang Jingjing, Hong Xiaozhen, Xu Xianguo, He Ji, Zhu Faming

Abstract excerpt

Background: RhD is the most important and complex blood group system because of its highly polymorphic and immunogenic nature. RhD variants can induce immune response by allogeneic transfusion, organ transplantation, and fetal immunity. The transfusion strategies are different for RhD variants formed by various alleles. Therefore, extensive investigation of the molecular mechanism underlying RhD variants is...

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Identifiers

PMID: 34867989
DOI: 10.3389/fimmu.2021.755661
PMCID: PMC8633534

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