Article
Correlation of the BRAF V600E mutation in hairy cell leukaemia with morphology, cytochemistry and immunophenotype.
International journal of laboratory hematology - 1 Aug 2012
Langabeer S E, O'Brien D, Liptrot S, Flynn C M, Hayden P J, Conneally E, Browne P V, Vandenberghe E
Abstract excerpt
Hairy cell leukaemia (HCL) has distinct clinical, morphological and immunophenotypic features with no recurrent cytogenetic or molecular abnormalities reported until the recent description of the BRAF V600E mutation in patients with classical HCL. The incidence of this mutation was sought in 27 patients with either classical HCL or HCL variant by an allele-specific PCR approach and findings related to morphology,...
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