Correlation of the BRAF V600E mutation in hairy cell leukaemia with morphology, cytochemistry and immunophenotype.

doi:10.1111/j.1751-553X.2012.01402.x

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Article

Correlation of the BRAF V600E mutation in hairy cell leukaemia with morphology, cytochemistry and immunophenotype.

International journal of laboratory hematology - 1 Aug 2012

Langabeer S E, O'Brien D, Liptrot S, Flynn C M, Hayden P J, Conneally E, Browne P V, Vandenberghe E

Abstract excerpt

Hairy cell leukaemia (HCL) has distinct clinical, morphological and immunophenotypic features with no recurrent cytogenetic or molecular abnormalities reported until the recent description of the BRAF V600E mutation in patients with classical HCL. The incidence of this mutation was sought in 27 p...

Topics

Adult
Aged
Aged, 80 and over
Bone Marrow Cells
Diagnosis, Differential
Female
Genetic Variation
Histocytochemistry
Humans
Immunophenotyping
Leukemia, Hairy Cell
Male
Middle Aged
Mutation
Proto-Oncogene Proteins B-raf
Retrospective Studies

Source

Open in PubMed

Identifiers

PMID: 22313586
DOI: 10.1111/j.1751-553X.2012.01402.x

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-22313586-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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