Article
Urocortin-dependent effects on adrenal morphology, growth, and expression of steroidogenic enzymes in vivo.
Journal of molecular endocrinology - 1 Apr 2012
Riester Anna, Spyroglou Ariadni, Neufeld-Cohen Adi, Chen Alon, Beuschlein Felix
Abstract excerpt
Urocortin (UCN) 1, 2, and 3 are members of the corticotropin-releasing factor (CRF) family that display varying affinities to the CRF receptor 1 (CRFR1 (CRHR1)) and 2 (CRFR2 (CRHR2)). UCNs represent important modulators of stress responses and are involved in the control of anxiety and related disorders. In addition to the CNS, UCNs and CRFRs are highly expressed in several tissues including the adrenal gland,...
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