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Article

A common genetic background could explain early-onset Crohn's disease.

Medical hypotheses - 1 Apr 2012

Bianco Anna Monica, Zanin Valentina, Girardelli Martina, Magnolato Andrea, Martelossi Stefano, Martellossi Stefano, Tommasini Alberto, Marcuzzi Annalisa, Crovella Sergio

Abstract excerpt

Crohn's disease (CD) is a multifactorial disease, in which environmental, microbial and genetic factors play important roles. CD is characterized by a chronic granulomatous inflammation by necrotic scarring with aspects of full-thickness wall. In spite of affecting mainly young adults, sometimes, CD can be present in the first year of life (early onset Crohn disease, EOCD) showing an unpredictable course and...

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PMID: 22309886
DOI: 10.1016/j.mehy.2012.01.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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