Article
Anticipation in familial Crohn’s disease
1 Feb 1998
Abstract excerpt
BACKGROUND: Offspring with a family history of Crohn's disease have an earlier age of onset than their parents. This might be due to genetic anticipation, characterised by earlier and/or more severe disease in subsequent generations. AIMS: To investigate the possibility of genetic anticipation in affected parent-child pairs with Crohn's disease from France and Belgium. PATIENTS AND METHODS: In a cohort of 160...
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