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Article

Modulation of function in a minimalist heme-binding membrane protein.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry - 1 Apr 2012

Shinde Sandip, Cordova Jeanine M, Woodrum Brian W, Ghirlanda Giovanna

Abstract excerpt

De novo designed heme-binding proteins have been used successfully to recapitulate features of natural hemoproteins. This approach has now been extended to membrane-soluble model proteins. Our group designed a functional hemoprotein, ME1, by engineering a bishistidine binding site into a natural...

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PMID: 22307279
DOI: 10.1007/s00775-012-0876-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22307279-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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