Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of MIF, CD40, and CD226 polymorphisms on risk of rheumatoid arthritis.

Molecular biology reports - 1 Jun 2012

Liu Ruiping, Xu Nanwei, Wang Xinxiang, Shen Li, Zhao Gongyin, Zhang Hui, Fan Weimin

Abstract excerpt

Macrophage migration inhibitory factor (MIF) is a key pro-inflammatory mediator. It plays an important role part in the pathogenesis of several inflammatory and immune diseases. A functional single nucleotide polymorphism (SNP) of MIF -173 G/C is known to influence MIF promoter activity in T lymphoblast cell lines and is associated with a higher serum MIF level. The CD40 is also crucial for some relevant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation, T-Lymphocyte
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to CD40 Antigens

Share to Intramolecular Oxidoreductases

Share to Linkage Disequilibrium

Share to Macrophage Migration-Inhibitory Factors

Share to Odds Ratio

Source

Identifiers

PMID: 22302395
DOI: 10.1007/s11033-012-1518-y

Genes

MIF
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of MIF, CD40, and CD226 polymorphisms on risk of rheumatoid arthritis.PMID 22302395Read ↗

Associations between circulating macrophage migration inhibitory factor (MIF) levels and rheumatoid arthritis, and between MIF gene polymorphisms and disease susceptibility: a meta-analysis.Semantic proximity Read ↗

The Role of MIF-173G/C Gene Polymorphism in the Susceptibility of Autoimmune Diseases.Semantic proximity Read ↗

Association of MIF-173G/C and MBL2 codon 54 gene polymorphisms with rheumatoid arthritis: a meta-analysis.Semantic proximity Read ↗

The -173 G/C polymorphism of the MIF gene and inflammatory bowel disease risk: a meta-analysis.Semantic proximity Read ↗

Association of MIF-173 gene polymorphism with inflammatory bowel disease in Chinese Han population.Semantic proximity Read ↗

Macrophage migration inhibitory factor promoter polymorphisms are associated with disease activity in rheumatoid arthritis patients from Southern Mexico.Semantic proximity Read ↗

Macrophage migration inhibitory factor (MIF): genetic evidence for participation in early onset and early stage rheumatoid arthritis.Semantic proximity Read ↗

Contribution of the -173 G/C polymorphism of macrophage migration inhibitory factor gene to the risk of inflammatory bowel diseases.Semantic proximity Read ↗

Influence of the MIF polymorphism -173G > C on Turkish postmenopausal women with osteoporosis.Semantic proximity Read ↗

Macrophage migration inhibitory factor gene: influence on rheumatoid arthritis susceptibility.Semantic proximity Read ↗

A Macrophage Migration Inhibitory Factor Polymorphism Is Associated with Autoimmune Hepatitis Severity in US and Japanese Patients.Semantic proximity Read ↗

A polymorphism in the macrophage migration inhibitory factor gene is involved in the genetic predisposition of Crohn's disease and associated with cumulative steroid doses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.