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Article

Cognitive function in health and disease: the role of epigenetic mechanisms.

Neuro-degenerative diseases - 1 Jan 2012

Mungenast Alison E, Tsai Li-Huei

Abstract excerpt

Epigenetic mechanisms regulate the interaction between the genome and the environment and have been implicated in the etiology of various brain diseases. One type of epigenetic modification, histone acetylation, is dynamically altered during memory formation. Histone acetylation is regulated by the activities of histone deacetylase (HDAC) and histone acetyltransferase enzymes. The use of HDAC inhibitors has...

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Identifiers

PMID: 22301371
DOI: 10.1159/000334602

Genes

HDAC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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