Article
Mutational robustness of gene regulatory networks.
PloS one - 1 Jan 2012
van Dijk Aalt D J, van Mourik Simon, van Ham Roeland C H J
Abstract excerpt
Mutational robustness of gene regulatory networks refers to their ability to generate constant biological output upon mutations that change network structure. Such networks contain regulatory interactions (transcription factor-target gene interactions) but often also protein-protein interactions between transcription factors. Using computational modeling, we study factors that influence robustness and we infer...
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