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Article

The robustness and evolvability of transcription factor binding sites.

Science (New York, N.Y.) - 21 Feb 2014

Payne Joshua L, Wagner Andreas

Abstract excerpt

Robustness, the maintenance of a character in the presence of genetic change, can help preserve adaptive traits but also may hinder evolvability, the ability to bring forth novel adaptations. We used genotype networks to analyze the binding site repertoires of 193 transcription factors from mice...

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Identifiers

PMID: 24558158
DOI: 10.1126/science.1249046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-24558158-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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