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Article

Genetic polymorphisms in fatty acid metabolism genes and colorectal cancer.

Mutagenesis - 1 Mar 2012

Crous-Bou M, Rennert G, Salazar R, Rodriguez-Moranta F, Rennert H S, Lejbkowicz F, Kopelovich L, Lipkin S M, Gruber S B, Moreno V

Abstract excerpt

Colorectal cancer (CRC) is a leading cause of cancer death worldwide. Epidemiological risk factors for CRC included dietary fat intake; consequently, the role of genes in the fatty acid biosynthesis and metabolism pathways is of particular interest. Moreover, hyperlipidaemia has been associated with different type of cancer and serum lipid levels could be affected by genetic factors, including polymorphisms in...

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Identifiers

PMID: 22294764
DOI: 10.1093/mutage/ger066
PMCID: PMC3269001

Genes

LIPC
PPARG

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