Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stanniocalcin-1 Rescued Photoreceptor Degeneration in Two Rat Models of Inherited Retinal Degeneration

31 Jan 2012

Abstract excerpt

Oxidative stress and photoreceptor apoptosis are prominent features of many forms of retinal degeneration (RD) for which there are currently no effective therapies. We previously observed that mesenchymal stem/stromal cells reduce apoptosis by being activated to secrete stanniocalcin-1 (STC-1), a multifunctional protein that reduces oxidative stress by upregulating mitochondrial uncoupling protein-2 (UCP-2)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Photoreceptor and optogenetics research
Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22294148
DOI: 10.1038/mt.2011.308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stanniocalcin-1 Rescued Photoreceptor Degeneration in Two Rat Models of Inherited Retinal DegenerationPMID 22294148Read ↗

Single Cell RNA Sequencing Analysis of Mouse Retina Identifies a Subpopulation of Muller Glia Involved in Retinal Recovery From Injury in the FCD-LIRD ModelSemantic proximity Read ↗

Amelioration of Photoreceptor Degeneration by Intravitreal Transplantation of Retinal Progenitor Cells in RatsSemantic proximity Read ↗

Generation of a Retina Reporter hiPSC Line to Label Progenitor, Ganglion, and Photoreceptor Cell TypesSemantic proximity Read ↗

Photoreceptor protection by cardiotrophin-1 in transgenic rats with the rhodopsin mutation s334ter.Semantic proximity Read ↗

Transplantation of Derivative Retinal Organoids from Chemically Induced Pluripotent Stem Cells Restored Visual FunctionSemantic proximity Read ↗

A new immunodeficient retinal dystrophic rat model for transplantation studies using human-derived cells.Semantic proximity Read ↗

Retinal organoids with X-linked retinoschisis RS1 (E72K) mutation exhibit a photoreceptor developmental delay and are rescued by gene augmentation therapy.Semantic proximity Read ↗

Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degenerationSemantic proximity Read ↗

Retina Organoid Transplants Develop Photoreceptors and Improve Visual Function in RCS Rats With RPE DysfunctionSemantic proximity Read ↗

Neuroprotective Effect of Intraperitoneal Humanin-G in Retinal Degeneration of Royal College of Surgeons RatsSemantic proximity Read ↗

Effect of targeted expression of clusterin in photoreceptor cells on retinal development and differentiationSemantic proximity Read ↗

Increased expression of catalase and superoxide dismutase 2 reduces cone cell death in retinitis pigmentosa.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.