Article

Neuroprotective Effect of Intraperitoneal Humanin-G in Retinal Degeneration of Royal College of Surgeons Rats

2026-03-24

Abstract excerpt

This study aimed to examine whether Humanin-G (HNG), a mitochondrial derived peptide with cytoprotective properties, could improve the retinal function and gene expression profiles after intraperitoneal injections to Royal College of Surgeons (RCS) rats with Retinal Pigment Epithelium (RPE) dysfunction and retinal degeneration. Starting at postnatal day 21 (p21), RCS rats received twice a week intraperitoneal inje...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a94b41c4-ce32-5ca7-be82-87a3d2c9b059
DOI: 10.64898/2026.03.20.713049

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Neuroprotective Effect of Intraperitoneal Humanin-G in Retinal Degeneration of Royal College of Surgeons RatsDOI 10.64898/2026.03.20.713049Read

Neuroprotective Effect of Intraperitoneal Humanin-G in Retinal Degeneration of Royal College of Surgeons RatsSemantic proximity Read

Polarized RPE Secretome Preserves Photoreceptors in Retinal Dystrophic RCS RatsSemantic proximity Read

Subretinal delivery of GMP-grade human neural progenitor cells protect vision in rat model of retinal degeneration and survive in minipigsSemantic proximity Read

Experimental Study of the Biological Properties of Human Embryonic Stem Cell-Derived Retinal Progenitor Cells.Semantic proximity Read

A new immunodeficient retinal dystrophic rat model for transplantation studies using human-derived cells.Semantic proximity Read

Comprehensive transcriptomic analysis reveals canonical and novel pathways modulated by nanoceria in mammalian retinal degenerationSemantic proximity Read

Retina Organoid Transplants Develop Photoreceptors and Improve Visual Function in RCS Rats With RPE DysfunctionSemantic proximity Read

Syn3, a newly developed cyclic peptide and BDNF signaling enhancer, ameliorates retinal ganglion cell degeneration in diabetic retinopathySemantic proximity Read

Mechanisms of protection of retinal pigment epithelial cells from oxidant injury by humanin and other mitochondrial-derived peptides: Implications for age-related macular degenerationSemantic proximity Read

Legacy of the RCS rat: impact of a seminal study on retinal cell biology and retinal degenerative diseases.Semantic proximity Read

Oral 8-aminoguanine against age-related retinal degenerationSemantic proximity Read

[New drug therapy for retinal degeneration].Semantic proximity Read