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Article

Effect of targeted expression of clusterin in photoreceptor cells on retinal development and differentiation

15 May 1999

Abstract excerpt

Clusterin expression is increased in tissues undergoing apoptosis, including neurodegenerative retina, but the causal relationships remain to be clarified. To test the hypothesis that overexpression of clusterin could induce apoptosis in neurons, transgenic mice were generated in which rat clusterin transgene was expressed in photoreceptor cells under the transcriptional control of the human interphotoreceptor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 10212140
DOI: 10.1242/jcs.112.10.1455

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