Article

Transplantation of Derivative Retinal Organoids from Chemically Induced Pluripotent Stem Cells Restored Visual Function

2024-09-13

Abstract excerpt

<title>Abstract</title> <p>As an emerging type of pluripotent stem cells, chemically induced pluripotent stem cells (CiPSCs) avoid the risks of genomic disintegration by exogenous DNAs from viruses or plasmids, providing a safer stem cell source. To verify CiPSCs’ capacity to differentiate into retinal organoids (ROs), we induced CiPSCs from mouse embryonic fibroblasts by defined small-molecule compounds and succ...

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Literature Corpus work: 5ee4bc24-8a2c-5099-8621-2512ee1b9903
DOI: 10.21203/rs.3.rs-4568327/v1

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