Article
CYP1A1 gene polymorphisms: lack of association with breast cancer susceptibility in the southern region (Madurai) of India.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Kiruthiga P V, Kannan M Rajesh, Saraswathi C, Pandian S Karutha, Devi K Pandima
Abstract excerpt
The cytochrome P 450 1A1 gene encoding a phase I metabolic enzyme appears to be a candidate for breast cancer risk. It is involved in the phase I detoxification of polycyclic aromatic hydrocarbons (PAHs) and 2-hydroxylation of estrogens and mammary carcinogens into 2-hydroxy catechol metabolites....
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