Article
Lack of Association between CYP1A1 M2 and M4 Polymorphisms and Breast Carcinoma in Jordanian Women: a Case-Control Study.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016
Amrani Iman, Bulatova Nailya, Awidi Abdalla, Yousef Al-Motassem, Melhem Jamal Masad, Al-Masri Mahmoud, Tahoun Laila Abu
Abstract excerpt
BACKGROUND: CYP1A1 is a candidate gene for low-penetrance breast cancer susceptibility, as it plays an important role in the metabolism of carcinogens and estrogens. PURPOSE: The objective of this study was to assess the association between M2 (A2455G, Ile462Val) and M4 (C2453A, Thr461Asn) polymorphisms in CYP1A1 and breast cancer risk among Jordanian women and in subgroups stratified by menopausal status and...
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