Article
Cytochrome P4501A1 genetic polymorphisms and breast cancer risk in Nigerian women.
Breast cancer research and treatment - 1 Dec 2005
Okobia Michael, Bunker Clareann, Zmuda Joseph, Kammerer Candace, Vogel Victor, Uche Emmanuel, Anyanwu Stanley, Ezeome Emmanuel, Ferrell Robert, Kuller Lewis
Abstract excerpt
In this case-control study based on 250 women with breast cancer and 250 age-matched controls, we sought to evaluate the role of four polymorphic variants in the CYP1A1 gene in breast cancer susceptibility in Nigerian women. Heterozygosity for the CYP1A1 M1 genotype (CYP1A1 M1 [T/C]) was associated with a 21% reduced risk of breast cancer (OR = 0.79, 95% CI 0.46-1.40) while homozygosity for the genotype (CYP1A1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.